What Happens If You Drink On Accutane?

Accutane, a powerful medication for severe acne, has transformed countless lives with its remarkable results. Scientifically known as isotretinoin, the medication targets the root causes of severe acne by dramatically reducing oil gland size and oil production, combating bacteria, and easing inflammation. The medication is processed through the liver and may play a role in elevating liver enzymes in some patients.

This raises the question that is on many patients’ minds, especially teenagers: Can you drink while on Accutane? Read below for the considerations and conclusion.

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The Effects of Accutane on the Liver

Accutane is metabolized through the liver. Breaking down the medication can increase burden on the liver, which may lead to elevated liver enzymes in a small proportion of patients. Studies show that anywhere from 1% to 30% of patients can experience liver function abnormalities. Note: that is also why it is important to get baseline bloodwork done before starting Accutane, and to monitor it early on in your treatment course.

Need more guidance on how to take Accutane? Reach out to Honeydew today for a consultation with a licensed dermatologist.

Risks of Mixing Alcohol and Accutane


First, you should note that there is no harmful chemical interaction between alcohol and Accutane. The two substances don’t react into something that is more dangerous than the sum of each part.

However, alcohol is inherently harmful to your liver. If you are taking Accutane, and you happen to be a patient with the side effect of liver function abnormalities, by introducing alcohol you risk adding extra strain on your liver that could lead to serious damage.

As with most things, it becomes a question of dosage. If you are consuming alcohol in small moderation, it’s unlikely that you are going to experience extra dangers to your liver because of the alcohol. However, if you are binge drinking regularly, the damage to your liver from alcohol and Accutane could be greater than if you were consuming alcohol alone. You should not drink excessively while on Accutane.

If you do drink on Accutane, it’s important that you get regular blood work done to monitor your liver function and lipid profile. The results can help you understand when you are overdoing it. Additionally, it’s worth speaking to your healthcare provider about considering a lower dose of Accutane if you are worried about your alcohol consumption while on the medication.

The considerations of risk don’t stop at liver health.


Alcohol can impair judgment, both physically and mentally. Physically, alcohol can increase the likelihood of failing to use safe sex practices, which increases the chances of pregnancy. If you are a patient who can get pregnant, you have a responsibility to avoid pregnancy. Getting pregnant while on Accutane can lead to severe birth defects. If you are a biological male, you do not have to worry about your use of Accutane causing birth defects. The concentration of Accutane that is transmitted through sperm is negligible and will not create health risks to the fetus.

Mental Health

For those already navigating the emotional impacts of severe acne, consuming alcohol can exacerbate mental health challenges. It’s important to prioritize your mental health and to inform your healthcare provider of how you are feeling.

Skin Health

In general, consuming alcohol is bad for your skin.

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What Research Says: Studies on Accutane and Alcohol

Research sheds light on the complexities of combining Accutane and alcohol. Key findings consistently point towards the adverse effects of this combination, especially concerning liver health. Clinical studies emphasize that when patients on Accutane consume alcohol, their liver function can be significantly compromised, leading to a range of potential health issues.

Side effects, already a concern with Accutane alone, show an increased prevalence when alcohol is added to the mix. These findings are echoed by dermatologists and healthcare professionals who witness the real-world impacts of this combination. However, there remains a gap in research. More extensive, long-term studies are needed to fully understand the breadth and depth of the interactions between Accutane and alcohol. This lack of comprehensive data points to the need for caution and personalized guidance from healthcare professionals for anyone considering or currently on Accutane treatment.

Personal Stories and Testimonials

The journey of those who have mixed Accutane and alcohol is filled with varied experiences and pivotal lessons. Personal accounts reveal that drinking while on Accutane often led to aggravated side effects, ranging from intensified skin dryness to severe liver complications. These stories are not just warnings; they are real-life experiences underscoring the risks involved.

Recovery narratives offer a glimpse into the resilience of individuals and the potential consequences of straying from medical advice. These stories often end with a strong message: adhering to guidance from healthcare professionals is not merely a recommendation; it’s a pathway to safe and effective treatment. Those who have completed their Accutane journey frequently emphasize this, offering advice grounded in their experiences. The takeaway is clear: the importance of following medical advice cannot be overstated when it comes to managing treatment with such a potent medication.

Guidance from Healthcare Professionals

Dermatologists and healthcare professionals provide support and expertise for those on Accutane. They unanimously recommend minimizing alcohol use during treatment, citing the additional strain it places on the liver and the potential for exacerbating side effects. Regular check-ups and liver function tests are crucial, helping to monitor the body’s response to the treatment and ensuring safe continuation.

Professionals also emphasize the role of a balanced diet and a healthy lifestyle in complementing Accutane treatment. This includes not only avoiding alcohol but also being mindful of other dietary and lifestyle choices. When it comes to concerns about alcohol and Accutane, having an open and honest discussion with your doctor is key. They can provide personalized advice and help navigate any uncertainties.

The role of healthcare professionals in managing Accutane treatment extends beyond prescribing the medication. They are partners in your journey, providing guidance, support, and the expertise needed to navigate the complexities of treatment safely and effectively.

Focusing on Your Well-Being with Honeydew

Honeydew is well-versed in the complexities of managing Accutane treatment.

We connect patients with licensed healthcare professionals who offer individualized, expert guidance. If you’re wrestling through the challenges associated with this acne medication, set up an online consultation with Honeydew.